Archer further enhances biochip gFET design for advanced sensing

2 mins read

Archer Materials has developed a next generation biochip fabrication to better detect and control disease samples on a single graphene field effect transistor (“gFET”) design.

The design has been sent to a commercial foundry partner for a whole four-inch wafer run for validation.

The first-generation hardware and software in the system platform announced earlier this year was designed to run using a chip with single isolated gFETs as sensors, as gFETs offer an ultrasensitive approach to analyte detection over conventional electronic sensors used in current lab-on-a-chip devices.

Archer’s gFET design is seen as paving the way for an early biochip system platform that has single-device multiplexing, meaning the biochip technology would be able to sense different liquid samples to test for multiple diseases at once.

This more advanced design is a critical milestone in the commercialisation pathway for the biochip, which will potentially enable end-users to detect multiple diseases from one single chip.

The gFET design also has functional surfaces and components, for both the sensor and control of the biochip platform. There is also an integration of gFET design components that allow for the real-time fine tuning and control of the electronic properties of the graphene. This has the potential advantage of biosensors that are re-usable, leading to an extended device lifetime.

In addition, Archer has improved its biochip system platform testing capabilities to develop a more accurate sensor. The upgraded automated testing platform conducts both control software and readout hardware with improved efficiency. The software is also progressing towards automated data analysis, so end users can extract high quality data.

This more complex gFET design complements the proof-of-concept biosensing gFET announced in July 2023. The earlier design was submitted to a commercial foundry for a Multi-Project Wafer run, with the completed devices expected to be delivered by the end of 2023. Archer expects the advanced gFETs on a single four-inch wafer to be delivered by the additional commercial foundry partner by the end of 2023.

The advanced device designs have been submitted to a foundry in the Netherlands for a whole wafer run (the previous ‘simpler’ design was submitted to a foundry in Germany for a Multi-Project Wafer (“MPW”) run).

Commenting on the more advanced gFET design, Dr Mohammad Choucair, CEO of Archer, said, “Archer continues to build on the core of its biochip technology, the gFET, and this more advanced design not only improves the chip’s detection and control abilities for multiple diseases from one single chip, but it also extends its use-time and brings it closer towards commercialisation.

“We continue to add to our strategic partnerships within the semiconductor supply chain, and our new foundry partner, which has the new gFET design in hand for a whole wafer run, represents a key step in this path to commercialising the biochip.”